Tribulus has been widely used for sexual dysfunction in both; males and females. In China and India, the herb Tribulus terrestris has been touted as liver, kidney, urinary, and cardiovascular remedies. In Ayurvedic science, the herb is considered to be a general health tonic and urinary tract disinfectant .
The herb has been in use treating various health ailments such as -
- Urinary Genital Support
- Energy and stamina
- Libido and sexual behavior enhancer
- Longer orgasms and climaxes
- Uro-genital problems and infections
Tribulus has been marketed for such conditions because research performed in Bulgaria and Russia revealed that Tribulus increases the levels of hormones testosterone (by increasing luteinizing hormone), DHEA, and estrogen.
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Serving size: 2 Vegi caps
Servings per container: 30
Each 500 mg capsule contains: Gokshura
Dosage: 1-2 Capsules two times a day after meal or or as directed by your health practitioner.
The Tribulus is now being promoted as a booster for the purpose of increasing the low sex-drive. The drug has been used for this purpose since years in Ayurvedic medical science and also in Eastern Europe in the 1970's. Independent studies have revealed that Tribulus terrestris extract slightly elevates the hormonal levels, though leaving them in the normal state.
Some have studied the tonic properties of Tribulus terrestris and have compared that to the effects of ginseng, but these occur due to totally different mechanisms. It is also recorded that Tribulus terrestris elevates testosterone levels by increasing gonadotropin-releasing hormone (GnRH) which eventually, in turn stimulates the production of LH and follicle-stimulating hormone (FSH). Testosterone, besides its role in bodybuilding and increasing fertility and libido, the herb is also known to have a positive effect on bone marrow activity producing healthy red blood cell and the immune system.
One of the rodent studies found Tribulus to be useful as a sex booster. Sexual behavior and intracavernous pressure (ICP) were studied in both normal and castrated mice to further evaluate the role of Tribulus as an aphrodisiac. ICP refers to blood flow into the corpus cavernosa of the male reproductive organ penis.
In the study, adult rats had been divided into groups of eight each that included distilled water treated (normal and castrated), testosterone treated (normal and castrated) and Tribulus treated (castrated). Compared to the castrated control, treatment of castrated rats (with either testosterone or Tribulus extract) depicted increase in prostate weight and ICP. There was also a mild to moderate betterment in sexual behavior as evidenced by an increase in mounting frequency.
Tribulus terrestris has been studied in China and found to decrease the frequency of angina pectoris. Laboratory studies have revealed Tribulus to have antibiotic property and anti-tumor potentiality. Some of the researchers favor that there are some good evidences indicating Tribulus as enhancer for athletic performance. Tribulus terrestris can also lower cholesterols levels in bloodstream, and, in addition, Tribulus also have potential antioxidant properties. Tribulus can also lower down the blood pressure in rats with hypertension and also possesses blood sugar lowering effect. In some study in laboratory, cells found in saponins from tribulus terrestris inhibited the growth of a particular type of liver cancer cell line.
The fruit of Tribulus terrestris has been widely used in the Ayurvedic system of medicine for the treatment of many urinary disorders including urolithiasis. In order to evaluate the therapeutic claims described about this plant in traditional medicine, the ethanol extract of Tribulus fruit was tested for its action against artificially induced urolithiasis in albino rats. The results were favoring the herb.
Tribulus or Gokshura is one of Ayurveda’s best herbs for the kidneys. The herb is very effective in most of the urinary tract disorders. This is because it will promote the flow of urine, will cool and sooth the membranes of the urinary tract. The herb has also been used to remove urinary stones. Gokshura also stops bleeding. It is known to nourish and to strengthen the kidneys and reproductive organs. Tribulus has been used in the treatment of cystitis, renal calculi (kidney stones), incontinence, gout and impotence. Tribulus can also possess a mild diuretic action.
Some of the scholars suggest that Gokshura is a wonderful herb for prostate gland, which reduces many urinary discomforts and prostate problems by cleansing and work as tonic for the lower abdominal organs (i.e. urinary bladder, prostate etc.). It also has aphrodisiac properties as the herb is very well known to increase the quantity of semen and is useful in diseases of the genitourinary tract.
The mechanism of the herb is not fully understood but according to one theory, Tribulus terrestris may work by relaxing the smooth muscles and increasing blood flow into the corpus cavernosa for its erectile dysfunction and libido enhancing property. The relaxant effect observed is probably due to the increase in the release of nitric oxide from the endothelium and other nerve endings. Since Tribulus relaxes smooth muscles, this could be the reason why it gets us benefits in abdominal colic.
In Ayurveda, it is called as ‘rasayana’ meaning the rejuvenating the health. This improves the longevity of a person by offering immunity and strength to the body organs and muscles. With the combination of other rasayana drugs, this makes an excellent rejuvenating formula. The drug can also be used as single herb.
Ancient science of Ayurveda also describes that the herb has excellent positive effect on urinary tract soothing the ‘vrikka’ – the kidneys.
To investigate the effect of saponins from Tribulus terrestris on the renal carcinoma cell (786-0) in vitro, and inhibitory mechanisms. Effects of SIT on the cytotoxicity, morphological changes of apoptosis, cell cycle and expression of Bcl-2 protein in the 786-0 were tested respectively by MTT method, Wright and acridine orange stain assay, as well as flow cytometry (FCM). After the 786-0 was treated by STY, it was shown that: 1) A significant cytotoxic effect was observed by MTT assay; 2) Apoptosis-induced was viewed by Wright and acridine orange stain assay; 3) The distribution of 786-0 on S phase was increased; 4.) The expression of Bcl-2 protein and cyclin D1 was decreased. Saponins from tribulus terrestris can significantly inhibit the growth of 786-0 in vitro, partially, by apoptosis. (Experimental study of saponins from Tribulus terrestris on renal carcinoma cell line by Zhongguo Zhong Yao Za Zhi. 2005 Aug;30(16):1271-4)
Tribulus terrestris L. (Zygophyllaceae) have been used as an aphrodisiac agent in both; the Indian and Chinese traditional systems of medicine. Administration of Tribulus terrestris extract showed increased sexual behavior and intracavernous pressure both in normal and castrated mice and these effects were probably due to the androgen increasing property of the herb. The objective of the present study is to evaluate the effect of tribulus on nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) activity and androgen receptor (AR) immuno-reactivity in rat brain. 24 adult male Sprague-Dawley rats were distributed into two groups of 12 each. Group I was treated with distilled water and Group II was treated with tribulus terrestris at the dose of 5mg/kg body weight orally, once daily for 8 weeks. Following treatment transcardiac perfusion was done with Ringer lactate, 4% paraformaldehyde and 30% sucrose. The brain tissue was removed and sections of the paraventricular (PVN) area of hypothalamus were taken for NADPH-d and AR immunostaining. There was an increase in both NADPH-d (67%) and AR immunoreactivity (58%) in Tribulus terrestris treated group and these results were statistically significant compared to the control. Chronic treatment of Tribulus terrestris in rats increases the NADPH-d positive neurons and AR immunoreactivity in the PVN region. Androgens are known to increase both AR and NADPH-d positive neurons either directly or by its conversion to estrogen. The mechanism for the observed increase in AR and NADPH-d positive neurons in the present study is probably due to the androgen enhancing property of Tribulus terrestris. The findings from the present study add further support to the aphrodisiac claims of the herb. (Effect of Tribulus terrestris on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain in J. Ethnopharmacol. 2005 Jan 4; 96(1-2):127-32.)
Supplement Facts:
Serving size: 2 Vegi caps
Servings per container: 30
Each 500 mg capsule contains: Gokshura
Dosage: 1-2 Capsules two times a day after meal or or as directed by your health practitioner.
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